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Premature ejaculation, THE most common problem faced by at least 33% of men between the age of 20 to 50 years. Premature ejaculation is also called ‘early ejaculation’, ‘fast ejaculation’, ‘quick ejaculation’ by many. Though it is not a medical term, the problem is easily understood by any sex specialist or sexologist.

What is premature ejaculation?

Premature ejaculation or quick ejaculation is a condition when a man ejaculates before penetration or within a minute or two after penetration of penis during intercourse. Having sex for the first time or with a new partner can obviously cause anxiety and may result in premature ejaculation but if that keeps happening continuously for weeks and months, one must start looking for a good sexologist for premature ejaculation treatment.

I see that many men are looking to last longer in bed even though they don’t have premature ejaculation problem and some others with PE issue are looking for medicines, home remedies to treat their problem.” says Dr. Karthik Gunasekaran, popular sexologist from Chennai who meets dozens of men every week suffering from early ejaculation problem. Here, we bring you one medicine that can help treat premature ejaculation but you should take the information given here just for your educational purpose and not to experiment with drugs on your body.


What is Sertraline?

Sertraline is one of the many medicines used to treat premature ejaculation. Sertraline belongs to a family of drugs called the SSRIs (Selective Serotonin Reuptake Inhibitors). Usually SSRIs are prescribed to patients suffering from major depressive disorder (MDD), obsessive-compulsive disorder (OCD), post traumatic stress disorder (PTSD) etc. One of the side effects of sertraline is delaying ejaculation. Sertraline is popularly sold under the brand name ‘Zoloft’ in the USA and India.


What does research say about the effectiveness of sertraline?

A study done in 1998 that examined the effects of sertraline on 46 men with PE observed the following:

  1. 25mg of sertraline increased the ejaculation time from 1 minute to 7.6 minutes on an average.
  2. 50mg of sertraline increased the ejaculation time to an average of 13.1 minutes.
  3. 100mg of sertraline increased the ejaculation time to an average of 16.4 minutes.

Now, don’t go crazy and start taking sertraline without a doctor’s consultation. There are several other side effects of the medicine including anejaculation (no ejaculation at all), fatigue, erectile dysfunction, anxiety and other gastrointestinal disorders.

Other observed notes from different researches are:

  1. PE returned in some men after 6 months after stopping sertraline.
  2. On-demand usage of sertraline (4 hours before intercourse) also had the same effect as daily dosage but with limited side effects.

Harmful side effects of sertraline

  1. Black box warning by the FDA – taking sertraline may increase suicidal tendencies and induce thoughts of self harm. So, if you are in depression and having suicidal thoughts, you must absolutely stay from sertraline and must let your therapist know about the fact.
  2. Gastrointestinal problems – If you are suffering from bleeding internally (like colon) or ulcers, abstain from sertraline. It’s not good for you.
  3. Allergic reaction – If you are allergic to any other SSRIs, tell your doctor to check if sertraline is right for you.

Other side effects of sertraline

Common and non-harmful side effects include nausea, diarrhea, headache, anxiety, insomnia etc.

Alternatives to sertraline to treat premature ejaculation

Apart from sertraline, there are other SSRIs that may be prescribed to treat premature ejaculation:

  1. Fluoxetine (under the brand name Prozac)
  2. Citalopram (Celexa)
  3. Escitalopram (Lexapro)
  4. Paroxetine (Paxil)

There is another approach to treat premature ejaculation – prescribing alpha-blockers. Usually alpha-blockers are given to patients suffering from hypertension (high BP) and BPH (benign prostatic hyperplasia) or an enlarged prostate.

Few words of caution

See that 100mg of sertraline can delay ejaculation up to 16 minutes; that doesn’t mean that you can overdose yourself with 200mg or 300mg to run longer. That is going to take you to the emergency room rather than to the bedroom. We can’t urge enough to see a sexologist first and get the right dosage of sertraline or any other PE medicine and not to self medicate.

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